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  • Invokana | The Anti-Diabetic Medicine Gone Wrong

    Back in 2013, the U.S. Food and Drug Administration approved the release and sale of the drug Invokana. While still maintaining a proper diet and exercise, patients consume drugs like Invokana, or ”Canagliflozin”, in hopes of lowering the risks that accompany their type 2 Diabetes. The anti-diabetic drug serves as a sodium-glucose transport protein 2 inhibitor, meaning the drug lowers high sugar count by passing such through the patient’s urine. While Canagliflozin may control Type 2 Diabetes, such medicine still does not cure it. In fact, recent case studies have even shown that the drug may cause additional, and more serious health complications sometime after consumption.

    Downfalls of Consuming Invokana

    While the drug has been publicly available for four years, the FDA required the pharmaceutical company to display more warnings on the product’s labels and packaging. A more recent report by the FDA, published May 16, 2017, confirmed that the use of Invokana increases the risk of leg and foot amputations. Some serious side effects include:

      • Hypoglycemia
      • Hypotension (low blood pressure)
      • Genital Thrush (yeast infections found in both male and female
      • Increased Chances of Urinary Tract Infections
      • Increased Need to Use the Restroom (polyuria)
      • Constipation
      • Nausea
      • Dehydration / Increased Thirst; and
      • Increases in LDL Cholesterol

    The administration’s publication release was supported by their clinical trials. Such trials included patients with type 2 diabetes, some consumed Invokana, while some consumed placebos. The study found that leg and foot amputations occurred twice as often in patients treated with Invokana, in comparison to those who were treated with placebos. Unfortunately, some patients endured amputations to both legs. Such may even go as far as above the knee.

    Increasing Limb Amputation Risks

    Invokana, a type 2 diabetes medication, poses the threat of leg and foot amputations as stated by the U.S. Food and Drug Administration (FDA). In a safety alert announcement, FDA informed the general public, diabetes patients, and healthcare professionals, how patients are at risk of losing their toes and limbs, as supported by numerous studies. FDA released the safety caution in May of 2016. Per the FDA regulations, medicines containing such Invokana ingredient must henceforth prominently display “boxed warning” on packaging materials and all labels to warn consumers of the risk of potential leg amputation posed by the drug.


    It was not long after Invokana received approval from the U.S. Food and Drug Administration (FDA), that concerns began to emerge. One of the most alarming issues involved a suspected connection between the drugs and patient cases of diabetic Ketoacidosis - a condition characterized by dangerous levels of acid in the blood.

    Additional Side Effects

    Unfortunately, as more and more patients consume the medicine, the more their chances increase of developing additional complications to their health. Apart from already having type 2 diabetes, other seriously life-threatening risks may apply. Some of the major complications include the following:

      • Passing Out
      • Dehydration
      • Bone Fractures
      • Leg & Foot Amputations
      • Ketoacidosis (body produces excess blood acids (ketones)
      • Renal Toxicity
      • Kidney Failure
      • Depression
      • Heart Disease
      • Stroke
      • Nerve Damage; and
      • Blurred or Impaired Changes in Vision

    For patients who are hyperglycemic, increased risk of complications like blindness, kidney failure, amputations, and even death, can occur. In order to release glucose from one’s body, Invokana passes such through the user’s urine. This action causes more complications down the line. Such difficulties may include lack of proper hydration, which eventually may lead to low blood pressure dizziness, falls, and potential damage to the user’s kidneys and heart.
    Above all, your health is the most important factor.

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    In Business to Defend Your Best Interests

    If you or a loved one has experienced any of the above-mentioned symptoms, contact your doctor and attorney immediately. Talk to your doctor about your changes in health, and confer what may be the next best step in maintaining your health. By contacting your trusted Invokana Attorney, you may rest assured that your pain and suffering will not go un-noticed, nor un-discussed.

    (888) 529-3111

    A free consultation with a licensed and reputable Los Angeles Product Liability Attorney regarding your unique situation is available by calling:

    1-888-LAW-3111 Monday-Friday, 8am to 6pm.

    -- Jack Ter-Saakyan, Esq.

    Note: Attorney advertising. Nothing posted on this blog is intended, nor should be construed, as legal advice. Blog postings and hosted comments are available for general educational purposes only and should not be used to assess a specific legal situation. Nor does any comment on a blog post create an attorney-client relationship. The presence of hyperlinks to other third-party websites does not imply that the firm endorses those websites, their contents, or the activities or views of their owners.
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